Home » Uncategorized » – 2020/03/27: Ultra-deep Coverage Single-molecule R-loop Footprinting using SMRF-seq

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– 2020/03/27: Ultra-deep Coverage Single-molecule R-loop Footprinting using SMRF-seq

By in Uncategorized on .

Congrats to Maika and Stella for their work developing SMRF-seq!! This method permits S9.6-independent, strand-specific, near nucleotide resolution profiling of R-loops on single DNA molecules at ultra-deep coverage. Great work!

The paper is here: https://pubmed.ncbi.nlm.nih.gov/32105733/

 

See also the protocol version for SMRF-seq here: https://pubmed.ncbi.nlm.nih.gov/32681515/