Congratulations to Lionel, Stella, Yoong Wearn, Paul, Aparna, Shally, and Sandra for a fantastic effort!
Here’s the title of the paper and a few highlights. The whole story will come out June 30th online!!
Title: Prevalent, dynamic, and conserved R-loop structures associate with specific epigenomic signatures in mammals.
- Prevalent, conserved, and dynamic patterns of co-transcriptional R-loop formation
- R-loops associate with specific epigenomic signatures at promoters and terminators
- Terminal R-loops associate with an insulator and enhancer-like state
- Terminal R-loops define a new class of transcription terminators
Here are the links to the work:
NCBI link: http://www.ncbi.nlm.nih.gov/pubmed/27373332
Molecular Cell link: http://www.sciencedirect.com/science/article/pii/S1097276516301964