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Breaking news – June 2016: Newest R-loop paper is accepted in Molecular Cell. Congrats everyone!!

Congratulations to Lionel, Stella, Yoong Wearn, Paul, Aparna, Shally, and Sandra for a fantastic effort!

Here’s the title of the paper and a few highlights. The whole story will come out June 30th online!!

Title: Prevalent, dynamic, and conserved R-loop structures associate with specific epigenomic signatures in mammals.


  • Prevalent, conserved, and dynamic patterns of co-transcriptional R-loop formation
  • R-loops associate with specific epigenomic signatures at promoters and terminators
  • Terminal R-loops associate with an insulator and enhancer-like state
  • Terminal R-loops define a new class of transcription terminators

Here are the links to the work:

NCBI link: http://www.ncbi.nlm.nih.gov/pubmed/27373332

Molecular Cell link: http://www.sciencedirect.com/science/article/pii/S1097276516301964